Details Page for 2XWT

Antibody Structure Summary Page
Antibody Related Links

Antibody Name: SIGNALING PROTEIN / IMMUNE SYSTEM CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY

[COMPLEX]

Summary Information

PDB ID 2XWT
Antigen MOLECULE: THYROTROPIN RECEPTOR; FRAGMENT: LEUCINE RICH REPEAT DOMAIN, RESIDUES 22 - 260; SYNONYM: THYROID - STIMULATING HORMONE RECEPTOR, TSH - R; ENGINEERED: YES
Complex Yes
Light Chain Class ?
Heavy Chain Class ?
Source HOMO SAPIENS

Structural Information

CDRs Length Sequence
L1 13 SGSSSDIGSNYVS
L2 7 DNNKRPS
L3 11 GTWDSRLGIAV
H1 5 DNWIG
H2 17 IIYPGDSDTRYSPSFQG
H3 10 LDWNYNPLRY

Experimental Information

Experimental Method crystal
Resolution 1.90A
R-factor 17.94%
Fragment Type FAB
Deposition date 05-NOV-10