Details Page for 2VXS

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Antibody Name: CYTOKINE STRUCTURE OF IL - 17A IN COMPLEX WITH A POTENT, FULLY HUMAN NEUTRALISING ANTIBODY

[COMPLEX]

Summary Information

PDB ID 2VXS
Antigen MOLECULE: INTERLEUKIN - 17A; FRAGMENT: RESIDUES 20 - 155; SYNONYM: IL - 17A, IL - 17, CYTOTOXIC T - LYMPHOCYTE - ASSOCIATED ANTIGEN 8, CTLA - 8, INTERLEUKINE - 17A; ENGINEERED: YES;
Complex Yes
Light Chain Class ?
Heavy Chain Class ?
Source HOMO SAPIENS

Structural Information

CDRs Length Sequence
L1 13 TRSSGSLANYYVQ
L2 7 ANNQRPS
L3 11 YCQTYDPYSVV
H1 5 SYAMS
H2 17 AISGSGGSTYYADSVKG
H3 9 DLIHGVTRN

Experimental Information

Experimental Method crystal
Resolution 2.63A
R-factor 21.50%
Fragment Type FAB
Deposition date 09-JUL-08