Details Page for 2FX7

Antibody Structure Summary Page
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Antibody Name: IMMUNE SYSTEM CRYSTAL STRUCTURE OF HIV - 1 NEUTRALIZING HUMAN FAB 4E10 IN COMPLEX WITH A 16 - RESIDUE PEPTIDE ENCOMPASSING THE 4E10 EPITOPE ON GP41

[COMPLEX]

Summary Information

PDB ID 2FX7
Antigen MOLECULE: FRAGMENT OF HIV GLYCOPROTEIN (GP41); FRAGMENT: PEPTIDE EPITOPE OF 4E10; ENGINEERED: YES; MUTATION: YES
Complex Yes
Light Chain Class ?
Heavy Chain Class ?
Source HOMO SAPIENS

Structural Information

CDRs Length Sequence
L1 12 RASQSVGNNKLA
L2 7 GASSRPS
L3 9 QQYGQSLST
H1 5 TYALS
H2 17 GVIPLLTITNYAPRFQG
H3 18 EGTTGWGWLGKPIGAFAH

Experimental Information

Experimental Method crystal
Resolution 1.76A
R-factor 20.20%
Fragment Type FAB
Deposition date 03-FEB-06