Details Page for 1YY9

Antibody Structure Summary Page
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Antibody Name: IMMUNE SYSTEM / TRANSFERASE STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE EPIDERMAL GROWTH FACTOR RECEPTOR IN COMPLEX WITH THE FAB FRAGMENT OF CETUXIMAB / ERBITUX / IMC - C225

[COMPLEX]

Summary Information

PDB ID 1YY9
Antigen MOLECULE: EPIDERMAL GROWTH FACTOR RECEPTOR; FRAGMENT: UNP RESIDUES 25 - 642; SYNONYM: RECEPTOR TYROSINE - PROTEIN KINASE ERBB - 1; EC: 2.7.10.1; ENGINEERED: YES;
Complex Yes
Light Chain Class ?
Heavy Chain Class ?
Source MUS MUSCULUS, HOMO SAPIENS

Structural Information

CDRs Length Sequence
L1 11 RASQSIGTNIH
L2 7 YASESIS
L3 9 QQNNNWPTT
H1 5 NYGVH
H2 16 VIWSGGNTDYNTPFTS
H3 11 ALTYYDYEFAY

Experimental Information

Experimental Method crystal
Resolution 2.60A
R-factor 24.20%
Fragment Type FAB
Deposition date 24-FEB-05